Molecular mechanisms of sarcopenia
نویسندگان
چکیده
منابع مشابه
Sarcopenia: monitoring, molecular mechanisms, and physical intervention.
According to European Working Group on Sarcopenia in Older People (EWGSOP) sarcopenia includes both a loss of muscle strength and a decline in functional quality in addition to the loss of muscle protein mass. In order to develop strategies to prevent and treat sarcopenia, the risk factors and causes of sarcopenia must be identified. Age-related muscle loss is characterized by the contribution ...
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Despite general information that skeletal muscle mass is the largest organ in the body and despite increased awareness of the importance of skeletal muscle in biological function, methods and techniques for its routine assessment in humans are generally lacking. One important reason for the paucity of assessment tools is the relative lack of direct data on anatomical skeletal muscle mass in hum...
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Approximately 66% of the patients with rheumatoid arthritis (RA) have significant loss of cell mass (rheumatoid cachexia), mainly of skeletal muscle (rheumatoid sarcopenia). Sarcopenia is defined as muscle wasting associated with functional impairment. Patients with RA possess significant reduction in muscle strength, caused by muscle protein wasting, and loss of functionality. Various conditio...
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Current studies have shown that sarcopenia and nonalcoholic fatty liver disease (NAFLD) have similar pathophysiological profiles. The cooccurrence of sarcopenia and NAFLD has been observed in elderly patients. The actions of these conditions are linked, and their treatments are similar. Therefore, studies should be conducted on NAFLD-sarcopenia rather than on NAFLD or sarcopenia.
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ژورنال
عنوان ژورنال: Osteoarthritis and Cartilage
سال: 2016
ISSN: 1063-4584
DOI: 10.1016/j.joca.2016.01.020